Three-dimensional (3D) cell culture is an artificial environment in which the cells intermingle with the 3D surroundings. The global 3D cell culture market is growing at significant rate due to growing awareness, increasing focus on developing alternatives to animal testing and technological advancement, and new product launches. Different types of products contributed to the 3D cell culture market size. The market has witnessed high demand for scaffold-based 3D over the last few years, due to its ability to mimic in vivo condition.
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The 3D cell culture market has been segmented by application into drug discovery and toxicology testing, tissue engineering and regenerative medicine, and cancer and stem cell research. The cancer and stem cell segment account for the largest share in the market due to increasing prevalence of cancer and significant funding initiates for cancer research from private organizations and government.
The lack of infrastructure, high initial investment and lack of consistency in three-dimensional cell culture products are the major challenges for the growth of 3D cell culture market. Researchers face major problem in inserting scaffold into microplate wells; this inconsistency in the products reduces the reproducibility of results and thus reducing the efficiency of the research.
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The key challenge for the new entrants is the survival in capital intensive and highly regulated 3D cell culture industry. Research laboratories, institutes, and bio-pharmaceutical and biotechnology companies are rapidly adopting three-dimensional cell culture in practice replacing 2D cell culture; this decreases the competition among manufacturers of 3D cell culture products as buyer’s are in large number in the market.
Key players in the industry are investing in the development of innovative and advance products, which is strengthening their position in the market. In November 2012, Corning Incorporated acquired a majority of the Discovery Labware business from Becton, Dickinson and Company to expand its presence in the laboratory consumables market. Thermo Fisher Scientific Inc., Corning Incorporated, Merck & Co., Inc., Lonza Group, Reprocell, 3D Biotek, Emulate, Global Cell Solutions, Hamilton and Insphero are some of the key players offering 3D cell culture products.